Scientists from Stanford have found that cholesterol-lowering drugs have a beneficial effect on the functioning of blood vessels due to the effect on genes.
A positive effect affects the work of blood vessels, cells and vessels. It’s all about the effect of statins directly on the genes.
A detailed analysis showed that statin-based drugs interact with enzymes that regulate cholesterol levels in the liver. However, scientists have noticed another process – statins reduce the risk of blockage of the arteries and, as a result, prevent a heart attack.
In addition, the substances have reduced inflammation, which in fact reduces the likelihood of developing cancer. Writes about it Gazeta.ru with reference to the journal Nature Cardiovascular Research.
The beneficial effect on cells is associated with a decrease in the activity of genes that cause the transition of cells from a healthy state to a diseased one. A similar benefit has been seen in diabetic mice.
“If we can understand the mechanism, we can modify simvastatin so that it improves vascular function even more,” the experts noted.
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