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S&P 500 Today, August 25, 2026: Moderna Surges on Cancer Vaccine as DICK’S Sporting Goods Craters 29%

The index opened 23.80 points higher and added 0.62 in the six and a half hours that followed. Moderna took the constituent honours; the day's biggest faller was not a constituent at all.
August 25, 2026
6 mins read
New York Stock Exchange building facade with American flag, Wall Street, S&P 500 market update August 25 2026
The New York Stock Exchange on Wall Street. [Image Source: NBC News]

NEW YORK — For investors who loaded up on biotech last quarter, the melanoma data from Moderna Inc. arrived like a confirmation. For those who trusted DICK’S Sporting Goods to absorb the Foot Locker acquisition without breaking a sweat, it arrived like an invoice.

The gap between those two reactions was 45 percentage points in a single session. Only one of them happened inside the S&P 500.

The index closed at 7,677.28 on Tuesday, up 24.42 points or 0.32 per cent, having opened at 7,676.66 and travelled between 7,650.92 and 7,686.11. The Dow Jones Industrial Average added 160 points, or 0.30 per cent, to 53,579.94, and the Nasdaq Composite gained about 0.6 per cent, with technology and healthcare leading.

S&P 500, Tuesday 25 August 2026 · Source: Cboe Global Markets, the exchange record
MeasureLevelNote
Previous close (24 Aug)7,652.86The reference for the day’s change
Open7,676.66A gap of +23.80 points before a single hour had traded
Session high7,686.11Reached intraday, not held
Session low7,650.92Briefly below Monday’s close
Close7,677.28+24.42 points, +0.32%
Intraday range35.19 points0.46% of the index level
Net move after the open+0.62 pointsWhat six and a half hours of trading added
Figures are the exchange’s own record for the regular session ending 16:00 ET. The final row is the arithmetic that matters: 97.5 per cent of the day’s advance was already on the board at the opening bell.

There is one number in that table worth stopping on. The index opened 23.80 points above Monday’s close, and finished the day 0.62 points above where it opened. Ninety-seven and a half per cent of Tuesday’s gain was booked before the first hour of trading was out. Everything after that was a 35-point round trip that ended almost exactly where it began.

That is a different picture from a market grinding higher on conviction. It is a market that repriced overnight, on lower oil and softer bond yields, and then spent six and a half hours failing to add to it. The close came in 8.83 points below the session high.

Moderna’s melanoma readout, and the one big move the index owns

Moderna Inc. (MRNA) rose 14.36 per cent to close at $158.83, the largest single advance among S&P 500 constituents on Tuesday, on volume of 45.9 million shares. The catalyst was positive Phase 3 data for intismeran autogene, a personalised melanoma vaccine developed with Merck and Co. Analyst upgrades followed. Moderna publishes its clinical announcements through its own investor newsroom, which is where the primary release sits rather than in the summaries that followed it.

The claim being made for the data is larger than the day’s move. It is the first late-stage clinical proof of concept for mRNA applied to oncology, which is the thesis Moderna has been building since its Covid-19 vaccine established the delivery mechanism. Whether that survives contact with the full trial detail is a question for the readout itself, not for a one-day price change.

The biggest fall of the day was not in the index

DICK’S Sporting Goods (DKS) fell 30.68 per cent to $124.31 on 36.0 million shares, the sort of collapse that normally leads a market report. It is worth being precise about what it was: DICK’S is not an S&P 500 constituent, so however brutal the session was, it was not the index’s worst performer. That distinction belongs to Albemarle Corp. (ALB), down 5.89 per cent, which is a fall of an entirely different order.

The company reported second-quarter earnings that missed on both profit and revenue and cut full-year guidance. The deeper concern is the Foot Locker acquisition completed in September 2025: integration has underperformed, and same-store sales pointed to weakness in core retail that predates the deal. JPMorgan had trimmed its price target from $270 to $245 the day before the release, a preemptive move that proved nowhere near sufficient.

The day’s largest moves, and which of them the index actually owns · Closing prices, Cboe Global Markets
CompanyCloseChangeIn the S&P 500?
Moderna (MRNA)$158.83+14.36%Yes
Supermicro (SMCI)$38.46+9.35%Yes
Robinhood Markets (HOOD)$112.09+8.17%Yes
CDW Corp (CDW)$142.09+7.23%Yes
Bloom Energy (BE)$217.45+6.58%No
Liberty Global (LBTYB)$13.40−1.90%No
Albemarle (ALB)$133.18−5.89%Yes
Rubrik (RBRK)$92.65−5.50%No
Beta Technologies (BETA)$22.11−7.26%No
DICK’S Sporting Goods (DKS)$124.31−30.68%No
Membership checked against the current S&P 500 constituent list. Five of the ten names most often carried in Tuesday’s movers lists are not in the index at all, including the largest faller of the day.

Five of the ten names above are outside the index, which is the sort of detail that gets lost when a movers list is assembled from a screen rather than from the constituent file. Liberty Global’s B shares are the clearest case: they traded 6,273 shares on Tuesday, a volume at which the closing price is close to meaningless as a market signal.

Jackson Hole is still the week’s real event

Federal Reserve Chair Kevin Warsh speaks at the annual Economic Symposium in Wyoming on Friday. When his nomination was announced in February, gold fell ten per cent in a single session on expectations he would run tighter policy than his predecessor. Markets have since stopped treating him as the defining variable in each day’s move, and the Fed publishes its governors’ remarks as delivered, which is the text worth waiting for rather than the trailers.

Gold has already moved on it. Prices hit a 15-week high ahead of the speech, with spot gold settling near $4,641 an ounce, a level that reads less as confidence in rate cuts than as insurance against whatever he says. The gold rate today in India and globally reflects the same tension, an asset pricing geopolitical and monetary risk rather than macroeconomic confidence.

The trade backdrop, and an earnings surge resting on two names

Canada announced retaliatory steel duties on $20 billion of goods after Trump administration tariffs, and the White House signalled possible increases on autos, trucks and metals to 50 per cent. Walmart Inc. reported billions in tariff refunds in its most recent results alongside slower sales growth, the retailer collecting a windfall from trade policy while its underlying consumer shows strain. The national debt has crossed $40 trillion and Treasury yields remain elevated.

The earnings backdrop for the index is more constructive, and more concentrated. The S&P 500 is on track for its strongest earnings growth in years, with Alphabet Inc. and Amazon.com Inc. doing much of the aggregate heavy lifting, according to Fortune. An earnings surge led by two names is impressive and fragile in the same breath, and the concentration is the reason a 0.32 per cent index day can sit on top of a 45-point spread between individual stocks.

Where the index actually sits

Tuesday’s close leaves the S&P 500 roughly 139 points below its 52-week high of 7,816.70 and about 1,360 points above its 52-week low of 6,316.91. Those two distances are not comparable, and the index is not sitting in the middle of its range. It is sitting near the top of it, with about 1.8 per cent of headroom to the high and a very long way back to the low. Cboe Global Markets publishes the index’s own session record, which is the reference used throughout this report.

What Tuesday did not resolve

Whether Warsh signals a shift in Fed guidance on Friday. Whether DICK’S points to broader consumer discretionary strain or an isolated integration failure, a question its absence from the index makes harder rather than easier to read across. And whether Moderna’s Phase 3 readout produces a durable rerating of mRNA oncology assets or a single-session move that fades as the trial detail is absorbed.

One thing this report cannot tell you is how much of Tuesday’s opening gap was real demand and how much was positioning ahead of Friday. The exchange publishes what traded and at what price. It does not publish why.

Sam Bowman

Sam Bowman

Sam Bowman is journalist with The Eastern Herald, covering topics focused on technology, wellness, digital parenting, and business innovation.

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