Mbappe scored twice in the first eight minutes to take Paris Saint-Germain’s tally to 84 points, six ahead of second-placed Lens with two rounds to go.
And the defending champion also excels by a wide goal margin.
It is enough for the team of coach Christophe Galtier to draw against their Strasbourg host next Saturday to clinch the title.
Auxerre has 34 points, in 16th place, one point above the relegation zone, and receives Toulouse in the penultimate round.
Mbappe opened the scoring with a powerful shot into the top corner in the sixth minute, and two minutes later he added to the guest side’s advantage with a shot from 20 yards after a pass from Lionel Messi.
Mbappe took his tally to 28 league goals this season to top the goalscoring list, two ahead of Olympique Lyonnais striker Alexandre Lacazette.
Auxerre didn’t let go and Ryan Rafloson hit a ball that bounced off the crossbar, while goalkeeper Gianluigi Donnarumma stepped in to save Nuno da Costa’s attempt just before the break.
Lassen Senayoko pulled one back for Auxerre with a low shot six minutes into the second half, scoring his first-ever league goal.
The owner of the grounds imposed his control on the match, while Paris Saint-Germain relied on the counter-attacks of Mbappé and the brilliance of their goalkeeper Donnarumma, who saved him several times.
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